Shaw Nature Reserve is located off I-44, about 35 miles west of the Arch in downtown St. Louis. We are on I-44, Exit 253, Gray Summit. This is two exits west of Six Flags (Allenton/Eureka).
There are numerous side trips in the area of the Reserve that can be combined to your tour: Purina Farms, restaurants in Washington, Labadie, and Pacific, LaBarque Creek natural areas, antique shops in Washington and Eureka, wineries north of the Missouri River along Highway 94, the Black Madonna Shrine in Eureka, and Meramec State Park and Meramec Caverns near Sullivan.